The statement from the article, "Because E coli represents the majority of urinary isolates among nursing home residents, cranberry products remain an appealing UTI prevention strategy, but the evidence is conflicting” is supported by the cited resource by Jepson& Craig (2008)in their article “ Cranberries for preventing urinary tract infections.” Cranberry products according to Liska, Keern, and Maki (2016) have been used for decades in the treatment of UTIs among women. Some biochemical studies suggest that cranberries can prevent UTI by preventing the adhesion of bacteria to the walls of the bladder. The cranberry products include tablets, capsules, syrup, and juice. However, there is no consensus on the amount of dosage that is effective in preventing UTI. To test this theory, a randomized trial by Jepson& Craig (2008) was conducted to try and find out the efficacy of cranberry in the stoppage of repeat UTI.
In the review by Jepson& Craig (2008) the authors sought to review the evidence on the effectiveness of cranberry in UTI prevention in populations with neuropathic bladders, women with frequent UTIs, and older adults. The research was further extended to the effectiveness in the treatment of UTI in children. To ensure that the findings were correct, additional trials were incorporated into the study and led to a change in the overall conclusions. Across all the patients and populations studied, cranberry was not associated with the reduction of UTIs as compared to placebo. In the study, two of the trials involving women with recurring UTIs and other involving children failed to show the difference between antibiotics and cranberry in reducing the possibilities of repeat UTIs. The study reported that the adherence and adverse effects from cranberry products were highly variable. In order to maintain levels of cranberry that would be necessary for prevention of repeat UTI, women were be required to take 150 ml of the cranberry juice two times in a day. From the study, the recommendations were that physicians ought to counsel all their patients on the failure of the studies to demonstrate the effectiveness of cranberry in UTI prevention.
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In another trial by Barbosa-Cesnik et al. (2011), study results revealed that cranberry did not offer any protection against a repeat of UTIs among women. In the article a placebo- and double-blind studies were conducted on the effectiveness of cranberry juice on preventing a repeat of UTI among college women. The study was aimed at detecting the differences between the placebo and treated groups as detected in the unblended trials. The assumptions made were that 30% of the college women would have a repeat of UTI within the six months period. The general frequency of occurrence was estimated at 16.9% and this was witnessed across similar study groups. The college women that were active on cranberry intakes were slightly above the recurrence rates by 20 %. The authors then concluded that among the college students with acute UTIs, those that were drinking cranberry juice did not experience any decrease in the 6 months follow up period of a repeat UTI compared to those that took the placebo.
It is therefore clear from the evidence provided that cited resource “Cranberries for preventing urinary tract infections” by Jepson& Craig (2008) was accurate in supporting the original research. This is as evidence by Liska, Keern, and Maki (2016) and Barbosa-Cesnik et al. (2011) in their studies on how operative cranberry juice is in the stoppage of repeat UTI.
Source
Jepson, R. G., & Craig, J. C. (2008). Cranberries for preventing urinary tract infections. Cochrane Database Syst Rev , 1 (1).
References
Liska, D. J., Kern, H. J., & Maki, K. C. (2016). Cranberries and Urinary Tract Infections: How Can the Same Evidence Lead to Conflicting Advice?–. Advances in Nutrition , 7 (3), 498-506.
Barbosa-Cesnik, C., Brown, M. B., Buxton, M., Zhang, L., DeBusscher, J., & Foxman, B. (2011). Cranberry juice fails to prevent recurrent urinary tract infection: results from a randomized placebo-controlled trial. Clinical infectious diseases , 52 (1), 23-30.
