27 Oct 2022

94

Pathophysiology of Alzheimer’s Dementia

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Academic level: Master’s

Paper type: Essay (Any Type)

Words: 304

Pages: 1

Downloads: 0

Alzheimer's disorder is a progression of dementia, which is a condition that is associated with brain injury or disease that affects memory ( Ulep et al., 2018). People link Alzheimer's dementia to impairment in cerebral functioning and also call it chronic ongoing condition. Some of the signs of the disease include loss of social and occupational functioning, speech deficits, change in personality, and psychological disturbance. According to Gao (2019), individuals at risk of getting the condition are people who are old, with down syndrome, low IQ, or individuals with hyperlipidemia. The disease has no cure, and the life span of a patient diagnosed is eight years; however, with proper treatment, it slows the progression of the condition. People are yet to identify Alzheimer's origin, but they link the condition to genetics and environmental factors. The early sign of AD is associated with chromosomes 21, 14, and 1, which is responsible for amyloid precursor protein. 

The mind of a patient from Alzheimer's has two abnormalities that are the plaques and tangles that may have been caused by an accident or tangling of neurofibrillary. Clumps of protein known as plaques get in the way of brain cells, which cause death or damage of these cells, preventing communication. The tangling of neurofibrillary protein prevents the transportation of nutrients to the brain. In this case, the mind of a person shrinks. The diagnosis of Alzheimer's is primarily through tests that the health practitioner will use to make the judgment, but currently, there is no exact procedure for determination. Since there is no cure, doctors are mandated to treat the symptoms to reduce its progression. Medication used for patients is cholinesterase, which assists the cells in communicating in the brain. Memantine helps in slowing down the progress of the condition. Town and Hoffman (2019) argue that therapies are also encouraged for patients because it improves the functionality of the mind. A positive lifestyle has also proved to promote good health, especially for people with Alzheimer's dementia condition. 

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Reference 

Gao, S., Burney, H. N., Callahan, C. M., Purnell, C. E., & Hendrie, H. C. (2019). Incidence of Dementia and Alzheimer Disease Over Time: A Meta ‐ Analysis.  Journal of the American Geriatrics Society

Ulep, M. G., Saraon, S. K., & McLea, S. (2018). Alzheimer disease.  The Journal for Nurse Practitioners 14 (3), 129-135. 

Town, L., & Hoffman, K. (2019).  Dementia, Alzheimer's Disease Stages, Treatments, and Other Medical Considerations . Omega Press. 

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StudyBounty. (2023, September 16). Pathophysiology of Alzheimer’s Dementia.
https://studybounty.com/pathophysiology-of-alzheimers-dementia-essay

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