This topic is of great interest to me because renal hyperfiltration has been a common health issue worldwide. The condition is a typical feature of diabetes; therefore, the study regarding renal hyperfiltration is very important as it helps to add on the already existing knowledge concerning approaches to be taken in improving observations about blood pressure and glucose control to reduce high rates of glomerular filtration which may result into several health conditions such as diabetic renal disease ( Jhee et al. 2018) . The study is also critical in providing about knowledge concerning the treatment of the disease thus adding a new therapeutic knowledge to eradicate renal diseases in patients suffering vitamin D deficiency.
Method
The researchers conducted their study among the Korean NHANES, and 33,210 subjects that had normal renal function were used in the final analysis. The experiment was conducted used two variables which were severe Vitamin D deficiency, and renal hyperfiltration (RHF) defined as the serum 25-hydroxyvitamin D concentration <10 ng/mL and estimated glomerular filtration rate respectively. The glomerular filtration rate was measured after observing slight adjustments in factors such as height, age, sex, history of diabetes or hypertension ( Jhee et al. 2018) .
Delegate your assignment to our experts and they will do the rest.
Results
The researchers found the mean ± SD age of the research participants/subjects to be 48.1 ± 15.9 y while the total number of female research participants/subjects was 18,779 representing 56.5%. After the experiment, the researcher found out the estimated glomerular filtration rate to be negatively related to serum 25-hydroxyvitamin D concentrations in the analysis of multivariable linear regression, and this was represented by an expression β : −0.02; 95% CI: −0.02, −0.01; P < 0.001) ( Jhee et al. 2018) . In addition, the researchers categorized a total of 1637 participants/subjects into the RHF group, and they represented 4.9% while the prevalence of RHF was found to be significantly higher among the patients who were suffering from vitamin D deficiency as compared to the group that had vitamin D sufficiency and this was represented by 5.8% in comparison with 5.0% or p<0.001. On the other hand, a severe vitamin D deficiency was also found to be a significant risk factor for RHF in the multivariable logistic regression model, and this was represented by 2.41; 95% CI, 1.72, 3.43; P < 0.001 ( Jhee et al. 2018) .
Conclusion
The researchers concluded that a severe vitamin D deficiency is closely related to heightening prevalence of Renal Hyperfiltration (RHF) especially among the healthy adult population ( Jhee et al. 2018) . I have come to believe that vitamin D deficiency, renal hyperfiltration and the associated conditions such as kidney diabetes are among the worst health issues currently across the world. These diseases need proper medical attention and patients diagnosed with such diseases must be properly treated to save their lives. Regardless of the chronic nature of these diseases, improving supplementation of vitamin D to this affected population would significantly improve their clinical outcomes as well. Indeed this was good research since the researcher tried to limit research biases by deploying a large number of subjects which also helped to minimize errors which usually occurs with a small number of subjects. The research was funded by the American Society for Nutrition (ASN), and it greatly helped in the fight against renal hyperfiltration and renal diabetes since it added in new insights regarding the best approaches needed to fight the diseases.
Reference
Jhee, J. H., Nam, K. H., An, S. Y., Cha, M. U., Lee, M., Park, S., ... & Han, S. H. (2018). Severe vitamin D deficiency is a risk factor for renal hyperfiltration. The American journal of clinical nutrition , 108 (6), 1342-1351. https://academic.oup.com/ajcn/article-abstract/108/6/1342/5239885
