Indeed, hot flushes at age 45 are the major signs of menopause in addition to other symptoms like mood swings, fatigue, reduced sex drive, night sweats, and genitourinary symptoms. The ASCUS-to-SIL ratios can also reveal the status of women as to whether they are in their postmenopausal or perimenopausal stages of development. Mostly, ASCUS is a sign of the beginning of menopause and the vasomotor instability symptoms like hot flushes and night sweats only aggravate the condition ( Nwadike, 2019) . Additionally, I agree that menopause is accompanied by a range of other complications like being overweight, which eventually results in hypertension. Importantly, menopause starts at mid-forties, specifically at 45 years ( Nwadike, 2019) . At this stage, the body produces less quantity of oestrogen and progesterone hormones. Therefore, physicians must be keen on prescribing drugs for treating the condition to ensure that women can restore their previous quantities of oestrogen. However, I understand that excessive exposure to oestrogen can lead to breast cancer in women aged 45 years and above. The basic principle behind this idea is that the oestrogen hormone stimulates excessive cell growth and this can increase the chances of developing breast cancer. The medication regimes for treating menopause include hormone therapy, vaginal cream, gabapentin to reduce hot flushes, and clonidine that treats high blood pressure and relieves women of hot flushes ( Mayo Clinic, 2020) . Notably, these options must be cautiously prescribed to prevent breast cancer because the excessive exposure to oestrogen-related drugs exacerbates the situation. This brings us into an agreement that selective oestrogen receptor modulators (SERMs) are the best drugs for treating menopause while reducing the risk associated with the therapy. The SERMs can activate oestrogen receptors in certain tissues while blocking them in others. Therefore, they can effectively reduce the risk of breast cancer, uterine cancer, and thromboembolism.
References
Mayo Clinic. (2020). Menopause. Mayo Foundation for Medical Education and Research (MFMER). Retrieved from https://www.mayoclinic.org/diseases-conditions/menopause/diagnosis-treatment/drc-20353401
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Nwadike, V. R. (June 14, 2019). Healthline. Symptoms of Menopause from Ages 40 to 65. Retrieved from https://www.healthline.com/health/menopause/symptoms-of-menopause#second