3 Jan 2023

176

Treatment of Type II Diabetes Mellitus (T2DM)

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Academic level: College

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T2DM is a metabolic ailment that typically originates from the consumption of excess calories than energy spent in the body (Zhao, Xu, Wu & Yi, 2015). Type II diabetes is characterized by a progressive problem in the insulin secretory, which results from increased insulin resistance, thus increasing insulin demand in a person’s body to sustain the glucose homeostasis (Zhao et al., 2015). Failure of secretion of enough insulin by the pancreatic beta cells to compensate for the increased demand for insulin causes an elevation of the glucose levels in a person's blood. 

T2DM is correlated with Alzheimer's illness, as high blood sugars are linked to increased beta-amyloid proteins in a person’s brain that damage it (Zhao, et al., 2015). The patient using western drugs such as Aricept and Coumadin could help in controlling the blood glucose. Aricept is a drug efficient in the treatment of severe, moderate as well as mild cases of Alzheimer's condition. Aricept medications are effective though they are associated with side effects such as diarrhea, nausea, vomiting that increases with age and dose (Yiannopoulou, Anastasiou, Kyrozis & Anastasiou, 2019). Warfarin is the common anticoagulant, that effectively treats and prevents venous thrombosis, reduce symptoms of prosthetic heart valves, myocardial infarction, and arterial fibrillation (Ge, Zhang & Zuo, 2014). 

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Other major therapies employed in type II diabetes include herbal medicines, nutritional supplements, spiritual therapies, yoga, and other approaches to relaxation. According to Rao and Gan (2014), herbal medicine is the common therapy as the patient believes in its healthy and natural properties although improper and poor quality can result in adverse effects. Cinnamon cassia, is a spice used in various parts of the world, because of its anti-oxidant, antidiabetic, antioxidant, and lipid-lowering properties (Rao & Gan, 2014). Therefore, the consumption of cinnamon cassia by the 48-year old could help in decreasing the blood glucose because of its antidiabetic influence. 

Ginseng is a known herb whose biological properties include its ant stress, antitumor, and anti-inflammatory activities (Ge, Zhang & Zuo, 2014). Ge, Zhang, and Zuo (2018) confirm that ginseng is capable of performing neuroprotective activities in brain damages among patients with Alzheimer's condition. However, the constituents of ginseng tend to inhibit thromboxane formation as well as platelet aggregation, illustrating that ginseng is capable of reducing the warfarin efficacy in the patient. Therefore, caution is necessary for combining warfarin and ginseng in the patient. 

References 

Ge, B., Zhang, Z., & Zuo, Z. (2014). Updates on the clinical evidenced herb-warfarin interactions.  Evidence-Based Complementary and Alternative Medicine 2014

Rao, P. V., & Gan, S. H. (2014). Cinnamon: a multifaceted medicinal plant.  Evidence-Based Complementary and Alternative Medicine 2014 . http://downloads.hindawi.com/journals/ecam/2014/642942.pdf 

Yiannopoulou, K. G., Anastasiou, A. I., Kyrozis, A., & Anastasiou, I. P. (2019). Donepezil treatment for Alzheimer’s disease in chronic dialysis patients.  Case Reports i n Nephrology and Dialysis 9 (3), 126-136. 

Zhao, Y., Xu, G., Wu, W., & Yi, X. (2015). Type 2 diabetes mellitus-disease, diagnosis, and treatment. Journal of Diabetes Metabolism 6 (533), 2. https://www.longdom.org/open-access/type-2-diabetes-mellitus-disease-diagnosis-and-treatment-2155-6156-1000533.pdf 

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StudyBounty. (2023, September 16). Treatment of Type II Diabetes Mellitus (T2DM).
https://studybounty.com/treatment-of-type-ii-diabetes-mellitus-t2dm-essay

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