Kleiner, R. E., Dumelin, C. E., & Liu, D. R. (2011). Small-molecule discovery from DNA-encoded chemical libraries. Chemical Society Reviews , 40 (12), 5707-5717.
DNA is a complex molecule that is describable as one that carries and ensures genetic coding. This source significantly identifies DNA based on its structure and the formation of patterns forming what becomes the DNA structure. Arguably, the source notes that the determinant factors are the sugar Groups and the phosphate group. The deoxyribonucleic acid gives and is identifiable with the sugar that exists in it (Kleiner, 2011). In this case, deoxyribose is a ribose which is a modified sugar.
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Arguably according to this source, the two groups determine the formation and structure of the deoxyribonucleic acid. In essence, the two groups which are phosphates and sugars form patterns that lead to the creation of the genetic coding which determines the formation and the appearance of the molecules. The designs are unique according to the groups that form the patterns.
Mathur, D., & Medintz, I. L. (2017). Analyzing DNA nanotechnology: a call to arms for the analytical chemistry community.
Significantly, this source relates deoxyribonucleic acid to chemistry through its description. For instance, according to the source, DNA is a molecule whose composition includes two chains that intertwine around each other, forming double helix which bears contain instruction. Primarily, these instructions determine growth, functions, and development (Mathur, D., & Medintz, 2017). Also, the two strands contain simpler monomeric units that exist as nucleotides.
Mostly, this source goes further to open up a clear discussion beyond the existence of phosphate and sugar groups. The nucleotides are a compound of various elements including the adenine, thymine’s, cytosine, guanine and not only the sugars and phosphates. These four are describable as nitrogen-containing nucleobases. Additionally, the nucleotides become conjoined by covalent bonds. These bonds exist from both the nucleotides of the sugar groups as well as those of the phosphate groups. As a result of these covalent bonds, the formation of the double strands occurs, thus the DNA composition and the structure of these deoxynucleic acids.
Goodnow Jr, R. A., Dumelin, C. E., & Keefe, A. D. (2017). DNA-encoded chemistry: enabling the deeper sampling of chemical space. Nature Reviews Drug Discovery , 16 (2), 131.
This source points to the role of chemistry in deoxynucleic acid and the process of formation. Arguably, there is a precise examination that carbon atoms play an essential role. The phosphate group (PO 4+) and the hydroxyl ions (OH -) both have an attachment to their carbon atoms (Goodnow et al., 2017). Additionally, the strands arrange themselves in the opposite direction from each other. These two different but conjoined strands that exist in helix shape are held together by the hydrogen bonds. The nucleotides that are incredibly relevant in this formation comprise of three essential components. There is the nitrogenous base which is attached to a sugar molecule. The sugar molecule itself is attached to one or even several phosphate groups. Other components are the five-carbon sugar and the phosphate groups.
There is a need to understand the crucial role of the pentose sugar nitrogenous base and the phosphates. Phosphate exists as a residue. This residue has an attachment to hydroxyl groups of 5 carbon of a single sugar as well as the three carbon of the sugar within the next nucleotide. This process is dependent on how these components bond and the helix itself, which is the ultimate determinant of activities of cells that are a product of all these molecules in the form of patterns.
In conclusion, DNA carries and ensures genetic coding of an organism. DNA is based on its structure and the formation of patterns forming what becomes the DNA structure. DNA composition includes two chains that intertwine forming double helix which bears contain instruction. Primarily, these instructions determine growth, functions, and development Deoxynucleic acid structure is highly related to chemistry. The bonds are a crucial part of the structural formation. The DNA stores the genetic information that it passes as instruction. All cells in organisms depend on the information to grow, form, advance, or even function properly.
Reference
Goodnow Jr, R. A., Dumelin, C. E., & Keefe, A. D. (2017). DNA-encoded chemistry: enabling the deeper sampling of chemical space. Nature Reviews Drug Discovery , 16 (2), 131.
Kleiner, R. E., Dumelin, C. E., & Liu, D. R. (2011). Small-molecule discovery from DNA-encoded chemical libraries. Chemical Society Reviews , 40 (12), 5707-5717.
Mathur, D., & Medintz, I. L. (2017). Analyzing DNA nanotechnology: a call to arms for the analytical chemistry community.
