Patient
Mrs. Houth is a 65-year-old woman. She was rushed to Routh Health Center after being found lying unconscious in her car. Her son estimated that she could have been unconscious for over five hours. Upon admission, she was diagnosed with stage one Parkinson's disease, a condition that left her moderately weak. She was also diagnosed with arthritis and pre-existing Alzheimer. After being given various guidelines for managing Parkinson disease, Mrs. Houth was put on drugs to cholinesterase inhibitors to help treat her cognitive symptoms of Alzheimer.
The main factors that affected pharmacokinetics in Mrs. Houth included the molecular weight of the drug, dissolution degree, fat-soluble, and water solubility. For example, for best absorption, the drugs must have a reasonable degree of water solubility. According to Chisholm-Burns, Wells and Schwinghammer (2016) t he ability of the drug to dissolve easily will also significantly affect the drug's absorption. According to Rosenthal and Burchum (2018) t he drugs cell membrane too played a vital role in the dissolution. On the other hand, the pharmacodynamics of a drug can be affected by physiologic modifications as a result of ageing, other medicines, or genetic mutation ( Rosenthal & Burchum, 2018) . For example, Mrs. Houth's use of other drugs may have had an impact on the prescribed drugs for Alzheimer condition. The modifications do occur mainly because of binding levels in protein in the patient, receptor binding, or reduced receptor sensitivity.
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A Personalized Plan of Care
Daily routines are very critical for the patient and the caregiver. The patient will require a lot of guidance in planning their day that involves pleasant and structured activities that will play a role in reducing agitation. Well and adequately placed events will help in regulating the patient's blood pressure and mood changes. Any signs of irritation or boredom should be prompt to change the activity to an enjoyed alternative ( Epperly, Dunay & Boice, 2017) . For example, if the patient shows signs of boredom with playing cards, an option such as a short break or a movie should be introduced. A well planned out balanced diet should form part of the daily plans that will enable the patient to derive the best nutrients. Such will be essential to balance the patient's body acidity and alkaline levels.
References
Chisholm-Burns, M. A., Wells, B. G., & Schwinghammer, T. L. (2016). Pharmacotherapy principles and practice . McGraw-Hill.
Epperly, T., Dunay, M. A., & Boice, J. L. (2017). Alzheimer Disease: Pharmacologic and Nonpharmacologic Therapies for Cognitive and Functional Symptoms. American family physician , 95 (12).
Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers. St. Louis, MO: Elsevier.
