In this journal, metabolic acidosis seizures related to stroke will be discussed in relation to the learning I achieved during the clinical experience. One of the most common causes of metabolic acidosis is lactic acidosis that is mainly linked to high mortality rates. On the other hand, changes in pH and lactate levels can be identified in generalized epileptic attacks because of local muscle hypoxia that occurs during seizures.
A wide variety of metabolic disorders can lead to seizures related to stroke. Some are caused by a metabolic disturbance, including acidosis while others are caused by hypoglycaemia disturbances. In some instances, seizures get responsive when respective vitamins are administered, including folic acid and pyridoxine (Wyllie, Gupta, & Lachhwani, 2006). Metabolic acidosis is thus, caused by a situation where acids produced during metabolism accumulate. In addition, severe hypercapnia may lead to the fall in the pH of the tissues without affecting the cerebral energy state. In severe cases of tissue hypoxia and ischemia, there is an accumulation of lactic acid. Such is enhanced by dripping residual blood flow. In such instances, the concentration of lactate might rise to levels higher than the tissue wet weight, which in turn reduces the PH (Wyllie, Gupta, & Lachhwani, 2006). In instances where metabolic acidosis get to excessive levels, the functional and metabolic restitution is acutely affecting due to consequent deoxygenation and recirculation. Such instances might indicate symptoms of irreversible effects.
Delegate your assignment to our experts and they will do the rest.
As such, metabolic acidosis that leads to stroke, for instance in epileptic patients, occurs in the form of a collection of metabolic processes that lead to the modulation of membrane processes, including the ions transport (Wyllie, Gupta, & Lachhwani, 2006). It means that acidosis derails ions transportation and metabolic reactions. The damaging impacts of metabolic acidosis is enhanced in patients with severe brain ischemia. The treatment of the condition is achieved through alkali therapy that brings plasma pH to levels higher than 7.20. Alkali that is commonly applied in this process is sodium bicarbonate.
References
Wyllie, E., Gupta, A., & Lachhwani, D. (2006). The Treatment of Epilepsy: Principles & Practice. Lippincott Williams & Wilkins.
