Salmonella typhi is in the category of bacteria that infect the blood and the intestinal tract. It causes typhoid fever disease. The bacteria is common in areas where water and sewage treatment systems are inadequate or poorly maintained. The infection caused by Samonella typhi is passed from one host to another through contaminated drinking water and food. Furthermore, bacterial infection leads to instances of high fever, vomiting, and diarrhea. In some instances, it can be fatal, resulting in the death of the carriers.
As Salmonella typhi , I intend to reside in the intestinal tract and bloodstream of the host humans. These body parts have a high content of essential nutrients for growth. They also offer a favorable environment for survival. Favorable temperatures, acidity, and the availability of nutrients characterize the environment. All these factors contribute to more reproduction and survival within the host while developing more tactics to give resistance to any treatment that can be sought by the victims.
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I will do a variety of things to survive in the intestinal tract and blood of the host. I would use my ability to thrive within phagocytes. The phagocytes release DNA-damaging elements such as oxygen radicals that protect the human body from pathogens such as bacteria. Using SP12 type III, I will inject bacteria into the phagocytes. SP12 type III distorts the structure of the cells while preventing them from producing the DNA-damaging agents (Hardy, 2015). I would also use mutation as a way of adapting to the host environment. Changing my DNA composition will make it easier to avoid contact with phagocytes in the human body. Additionally, my ability to survive in amoeba will be an advantage to my continued development as I will be more resistant to antibiotics, disinfectants, and any treatments that might be used by humans for eradication or prevention of my spreading.
In a systematic process, I will pass through the lymphatic system of the host into their blood. I will also pass into the intestinal tract through ingestion by the hosts through contaminated water. Subsequently, I will produce toxins that will increase the permeability of the blood vessels while decreasing their tones. As I develop and survive in the host, I will lead to a variety of problems that will include upsetting the human body’s thermal regulation. The problems that I will cause on the humans will begin 6-30 days after I make entry into the body system (Cabello, Hormaeche, Mastroeni, & Bonina, 2012). The main problems that will be experienced are rash and fever. The fever that I will cause is significantly high and will increase gradually across several days to a high of 39-40 degrees Celsius. The rash entails rose-colored sports, especially on the abdomen and neck. I will also cause problems such as abdominal pain, headaches, weakness, and constipation. I can also cause mild problems in the form of diarrhea, confusion, and vomiting. Besides, untreated entry into the human body will lead to the problem of the perforation of the bowel, which can cause peritonitis. Peritonitis is an infection of the tissues of the lining of the abdomen, which can be fatal for the affected humans. Other problems that the affected persons can suffer would be dehydration.
My greatest fear would be the loss of the ability to fight against phagocytes in the human’s blood. In such a case, I might not be capable of surviving the conditions, mainly because of the immune system of the host. However, my life can end if the human host uses strong antibiotics against which I cannot develop any resistance. The strong antibiotics, including ceftriaxone can fight against me.
References
Cabello, F., Hormaeche, C., Mastroeni, P., & Bonina, L. (2012). Biology of Salmonella . Springer Science & Business Media.
Hardy, A. (2015). Salmonella Infections, Networks of Knowledge, and Public Health in Britain, 1880-1975. Oxford University Press.
