Throughout the body, the presence of proteins brings about rejuvenation within various organs and significant body tissues. This pertinent bio-molecule is present in our bone, hair, muscle, skin and practically every inch of the human body. Moreover, the role of proteins in the manufacturing of enzymes, which drive innumerable chemical reactions, is significant. It also makes up the component that is fundamental in the transport of oxygen to essential organs throughout the body: hemoglobin. Various doctors of varied discipline concur with the premise that more than 10,000 proteins make up the constituent form of an individual and furthermore, keep the person the way they are. Proteins are a significant part of human nutrition; doctors typically recommend a daily intake of proteins. This intake is well stipulated in the Institute of Medicine as an adult minimum of 0.8 grams for every body weight per kilogram. Other medical institutions also set an acceptable and wide range of protein intake and acceptability within the body. This range is from an approximate 9 to 34 percent of calories per day. Although there is little tangible information on the ideal protein intake, most hypotheses suggest a negative effect in the event of large consumptions. Commensurately, this paper discusses the detrimental effects of large protein intakes as exemplified in a bizarre case of overdose.
Recently, an Australian woman succumbed to death while taking exorbitant protein amounts from dietary supplements and food. In the event of anticipating a body building competition, this mom of two augmented her protein intake. Although doctors would have controlled her intake, they discovered an anomaly in her body that averted the proper metabolisms of protein. Commensurately, this slow protein breakdown led the woman to undergo intense suffering and eventually morbidity. The condition this woman was suffering from was known as urea cycle disorder and is one of the most dreadful diseases. According to numerous medical journals, a urea cycle disorder is normally a genetic disease that results from particular significant mutations; resulting in deficiencies on one of the six enzymes responsible for the proper functioning of the urea cycle. The biochemical steps of the urea cycle allow the proper disposal of nitrogen, which is a waste product of protein metabolism. This crucial process further converts the nitrogen into urea, safely disposed of in the action of urinating.
Delegate your assignment to our experts and they will do the rest.
While experiencing urea cycle disorder, nitrogen in the body accumulates to dangerous levels, forming ammonia, an extremely toxic substance in the human body. Ammonia onset leads to hyperammonemia, an elevated condition that results in large ammonia build-ups. Furthermore, increased ammonia presence in the blood leads to irreversible brain damage once it gets to the brain and a host of other complications in major organs within the body. Such complications result to comas or even death, as was the case of Meegan Hefford. In the United States, one in every 35,000 people is affected by this umbrella of genetic disorders that are rare. In reference to the National Urea Cycle Disorders Foundation, this circumstance happens in both adults and children and cases may take on varied forms of severity or mildness. Adults can also live with mild forms of this condition for years without realizing the disorder’s presence. In an article, doctors place the possibility of morbidity on protein related deaths on a number of reasons. One, a combination of illnesses or injury and large protein intakes impedes the process of ammonia expulsion. Another reason is the desire to achieve absolute fitness without properly understanding one’s body limits. Ultimately, although undiagnosed cases of urea cycle disorders usually appear in subtle symptoms, combinations such as vomiting, nausea, and the inability to think clearly should be clear markers of a depleted blood purification system.
