I. Topic
Narcolepsy is known as the neurological disease that causes chronic sleepiness and affects about 1 and every 2000 people (Campion, 2015). The persistence sleepiness through out the day makes it hard to focus and complete everyday activities. For those who have narcolepsy,they can go their entire life without being diagnosed due to the amount of limited research about the disease. Over the recent history is has become a topic of discussion to all those who have had questions about certain treatments alternatives, being that it is a life long disease. With recent research of clinicians to understand Narcolepsy and how it affects those who suffer from it, they have come to understand two types of it. Type 1 Narcolepsy is caused by an extensive loss of the hypothymatic neurons that produce orexin A & B (Campion, 2015). Type 2 is causes the same, but the cause of it is yet unknown to clinicians conducting research.
Those who suffer form Narcolepsy suffer from random sleepiness throughout out the day and staying awake during school, work, or periods of inactivity. During times where there is inactivity or where the body is relaxed it is hard to disassociated narcolepsy from those who appear just to be tired or restless due to a busy schedule. A distinguished difference between the two is that after a sleep cycle the patients seems to be well rested. There are also other indications of Narcolepsy to include Rapid-eye-movement-sleep. Patients who do not suffer from Narcolepsy have to stages of sleep. Non-voluntary rapid-eye-movement-sleep (NREM) and REM sleep. Those who have the disease go straight into REM sleep.
Delegate your assignment to our experts and they will do the rest.
Lastly we will discuss the treatment options, keeping in mind that there is nothing that can cure the disease entirely. However, it is treated through behavioral therapy and psychotherapy. There are also medications available to cure daytime sleepiness along with wake—rest-and sleep cycles a couple of times during the day for 15-20 minutes. The medications that are used is a low dosage anti-depressant. Also, at night a heavily sedative drug is giving to produce a deep REM sleep, which will reduce sleepiness through out the day.
Annotated Bibliography
Campion, E. W., & Scammell, T. E. (2015). Narcolepsy. The New England Journal of Medicine, 373 (27), 2654-2662. Retrieved from https://search-proquest-com.ezproxy2.apus.edu/docview/1752797053?accountid=8289
This article speaks on the known causes of Narcolepsy and discusses what Narcolepsy is and statics of those who have the disease across the world. It discusses specific symptoms specifically to those who are under the age of 18. It entails what details to look for to acquire a professional diagnosis and the difference between just being sleepy and actually having an issue. It then discusses symptoms that are associated with the diseases such as REM sleep cycles. It concludes the article with diagnosis and genetic features.
Barateau, L., Lopez, R., & Dauvilliers, Y. (2016). Treatment options for narcolepsy. CNS Drugs 30(5), 369-37-, doi;http://dx.doi.org.ezprozy1
The following treatment options are discussed those experiencing the type q and type 2 Narcolepsy. Treatment strategies for Type 1 include behavioral therapy and strategies and maintaining regular sleep patterns through out the night as well as different type of medications. Type 2 treatment options vary being that Type 1 is more significant. The same treatment options for NT1 are used due to no pharmacological studies shown in this study. This articles concludes with associated symptoms and treatment responses.
nocente, C. O., Lavault, S., Lecendreux, M., Dauvilliers, Y., Reimao, R., Gustin, M., & ... Franco, P. (2013). Impact of obesity in children with narcolepsy. CNS Neuroscience & Therapeutics , 19 (7), 521-528. doi:10.1111/cns.12105
This articles discusses the association of Narcolepsy in children who suffer from obesity. This gives a different look to see how Narcolepsy effects other portions of the body while deal with diseases. It study was conducted in 2008 until 2011 and surrounds all children under the age of 18. The case study evaluates 117 children, who have been diagnosed less than 3 years. 73 Students were given questionaries’ about daytime sleepiness and 72 were given the pediatric daytime sleepless questionnaire. The measurements were based of height and weight of students to include BMI. Our article concludes with results to support the hypothesis that children with Narcolepsy suffer from Obesity.
nocente, C. O., Gustin, M., Lavault, S., Guignard-Perret, A., Raoux, A., Christol, N., & ... Franco, P. (2014). Quality of life in children with narcolepsy. CNS Neuroscience & Therapeutics , 20 (8), 763-771. doi:10.1111/cns.12291
Quality of life in children with narcolepsy is expressed in this article with those living long healthy lives but needed emotional support as well. The struggles over operating in everyday life can become overwhelming for those who suffer. However, people who struggle from this are able to work any job they like, in any profession, if adequately on the proper medications and/or therapy. With children who become diagnosed early them being able to better cope throughput life is better.
L. Carter, C. Acebo, A. Kim, Patients’ journeys to a narcolepsy diagnosis, Sleep Medicine, Volume 14, 2013, Page e92, ISSN 1389-9457, http://dx.doi.org/10.1016/j.sleep.2013.11.193 .( http://www.sciencedirect.com/science/article/pii/S1389945713014081 )
Finding a diagnosis to Narcolepsy can be difficult depending on how long you have been living with it. Often times there is a 10-15 year onset from the time the first symptoms occur. This article studies patients who have been diagnosed with narcolepsy and how long it took them to receive full diagnosis. The study takes 252 patients conducted from 77 physicians, predominantly male and Caucasian They were to report whether symptoms were mild, moderate, or severe. 91% of the patient’s interviews noticed an increase in daytime sleepiness, while the rest noticed concentration levels decrease with the lack of functionality throughout the day. It ends with finding that patients who had symptoms took approximately two years to have a diagnosis from psysician.
Han, F., Lin, L., Warby, S. C., Faraco, J., Li, J., Dong, S. X., ... & Yan, H. (2011). Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Annals of neurology , 70 (3), 410-417.
This article is very critical is describing some aspect of history of Narcolepsy. One glaring point in this article is the cause of this condition among individuals in the great country of china. The article has presented statics which portrays China as one country which has high incidence of this condition as the study done in the 2009 has shown. The article is current hence has covered most of the contemporary issues.
