Response to Post #1
Daniel Falcocchio’s post has enhanced the understanding of Paget’s disease, a skeletal disorder by answering questions related to this disorder. The student has classified the disorder as a chronic bone disease considering that it mostly occurs in over 40-year-old individuals. A failure of the osteoclasts translates to more reabsorption of more bone forces osteoblasts to step in but it is overwhelmed since it is weak and brittle (Kravets, 2018). As a result, individuals who are suffering from Paget’s disease will develop curvature owing to weak bones during the formation. They may also complain of frequent headaches as osteoclasts weaken the bones in the skull. The post establishes the need to undergo X-rays to know if they have deformities.
Response to Post #2
This post focuses on the concept of fractures by establishing that doctors need to understand the nature of fractures in young children. Fractures are more prevalent in young children considering that most of them engage in dangerous play. Wang et al. (2019) assert that children are more likely to have fractures since their bones are very fragile in the early years. However, the right medical and therapeutic interventions play a significant role in correcting the fractures. In as much as the fracture may be corrected there is a likelihood that the healed area may develop a growth, which may cause stagnation in bone growth. In such a case, the growth may be removed and fat introduced to facilitate normal growth of bones.
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Response to Post #3
This post is Daniel Falcocchio’s reflection on the weekly discussion topic which revolved around Paget’s disease, a skeletal disorder. The discussion was very crucial as it brought new understanding especially since it focused on the relationship that exists between osteoclasts and osteoblasts. The need for osteoblasts to step in after osteoclasts have been destroyed cells paves the way for abnormalities some of which are irreversible (Cundy, 2017). Falcocchio seems fascinated by the fact that osteoblast failure is associated with the generation of more cells that are used to create bones. The new cells create brittle and porous bones, which are associated with curvatures and fractures.
References
Cundy, T. (2017). Paget’s disease of bone. Metabolism: Clinical and Experimental , 80, 5-14. https://doi.org/10.1016/j.metabol.2017.06.010
Kravets, I. (2018). Paget's disease of bone: Diagnosis and treatment. The American Journal of Medicine, 131 (11), 1298-1303. https://doi.org/10.1016/j.amjmed.2018.04.028
Wang, H., Feng, C., Liu, H., Liu, J., Ou, L., Yu, H., & Xiang, L. (2019). Epidemiologic features of traumatic fractures in children and adolescents: A 9-year retrospective study. BioMed Research International , 2019, 1-8. https://doi.org/10.1155/2019/8019063
