The measurement of a drug in a blood sample is intended to determine the existence of a certain drug or metabolite in human blood at a particular time. As much as blood sample tests are the most accurate way of determining whether a person is intoxicated, they are not conducted frequently since they require specialized equipment and highly-skilled personnel. Moreover, the fact that exposure of the sample to contaminants deteriorates the accuracy of the results further make blood tests highly sensitive. Before conducting a drug test on a blood sample, it is important to determine the time passed after the drug was consumed ( Moffat et al., 2011) . For example, the concentration of marijuana completely disappears in human blood after one month.
To determine the uncertainty of measurement of a drug test on a blood sample, we must determine the quantitative statement of the drug in the tested sample. We start by estimating the imprecision of the whole drug test. This will be important in ascertaining whether it is consistent with similar results ( Moffat et al., 2011) . This is in light with the internationally accepted standards and estimations that are used as a guidance in recognition of traceability of a single analyte such as the blood sample in our case. In that case, we can determine the uncertainty of measurement in our drug test by finding the combined uncertainty analytical factor that inherits all the associated uncertainties. This implies finding all the contributing variables that lead to the overall uncertainty of measurement. Then again, we have to validate individual factors that contribute to transitional precision. For example, this is obtained by making multiple tests of the same sample and making comparisons of their precision ( Copeland, 2013) . This way, associated bias is corrected or eliminated and we determine the overall measurement uncertainty.
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References
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Copeland, R. A. (2013). Evaluation of enzyme inhibitors in drug discovery: A guide for medicinal chemists and pharmacologists . Hoboken, N.J: Wiley.
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Moffat, A. C., Osselton, M. D., Widdop, B., & Watts, J. (2011). Clarke's analysis of drugs and poisons: In pharmaceuticals, body fluids and postmortem material . London: Pharmaceutical Press.
