Skin is the largest organ covering a human's body. It has many specialized structures and cells that help in the defense mechanism of the body. It has three main layers that include the hypodermis, dermis, and the epidermis, which play unique roles in the skin functioning. Generally, there are two skin types glabrous and hairy (Yadav et al., 2011). Lacking essential nutrients in the body, such as vitamins E and C, B complex, and beta-carotene causes one's skin to dry up.
Human skin protects the body from excessive water loss and against pathogens. Other roles of the skin are insulation, sensation, regulating temperature, synthesis, and storage of vitamin D. However, acne vulgaris, which is a chronic skin condition developing during adolescence and continuing to old age affects one's cosmetic look (Kozan et al., 2020). Acne lesions result from the increase in the production of sebum by the sebaceous glands and keratinization changes that result in the release of the inflammatory mediators (Kozan et al., 2020). Therefore, obtaining the best medication is necessary for the treatment of acne.
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Below is an experimental study assessing XYZ vitamin mix effectiveness in the treatment of acne vulgaris. The research question guiding this study is, how effective is XYZ vitamin mix in treating acne vulgaris? In this experiment, the dependent variable is acne, which depends on the XYZ vitamin mix tablet. XYZ tablets are the independent variable as, during the experimentation process, one easily controls or changes it, and they possess a direct impact on the dependent variable.
This study will involve sixty patients in the Acne Outpatients Clinic in one of the Dermatology hospitals in the country in the assessment of the XYZ effectiveness for acne treatment. GAGS (global acne grading system), photographic standards, and lesion counting are employed in the assessment of acne severity (Kozan et al., 2020). For the evaluation, two groups of 30 patients are formed. The first group uses a single tablet of XYZ vitamin mix twice a day. The second group consists of thirty patients who act as the control experiment. They neither apply nor consume any form of medication to confirm the changes in the first group are an effect of XYZ medication. Scores in the two groups are assessed at 0, 2, and 4 weeks, since the beginning of the experiment.
Patients included in the experimental study are 18 years and over, clinically diagnosed with acne vulgaris, employed only a single type of topical agent, not used the systematic retinoid for the last six months, and combined oral contraceptives (Kozan et al., 2020). Nevertheless, the patients were not to have used any topical acne preparation for the last three weeks and systematic steroids for the last one month. Patients below eighteen years, breast-feeding, pregnant, and having menstrual flow irregularity were excluded from the study (Kozan et al., 2020). Nonetheless, patients using cosmetic and systematic drugs other than the ones offered in the treatment are excluded from the study.
The most effective medication in treating acne should have keratolytic, anti-inflammatory, anti-bacterial, and wound healing features. Therefore, if the individuals in the experimental group using the XYZ vitamin mix had their lesions significantly reduced in number by the end of the four weeks, it is evident that the medication is effective in the treatment of acne vulgaris (Kozan et al., 2020). However, if the group using the XYZ tablet had no changes in the acne prevalence, shows that the XYZ is not effective in the treatment of acne. Nonetheless, one ought to be vigilant on the side effects that may develop if the patients react negatively towards the XYZ vitamin mix, which could be worsening of the condition, diarrhea, vomiting, or fever.
The method employed in including patients in the experimental study is likely to be limited by patients' forgetfulness on their underlying health conditions. Moreover, some questions involved in the study, which patients view as an invasion of privacy, such as those involving menstrual flow and contraceptives are likely to encourage lying (Kozan et al., 2020). Therefore, patients if not well evaluated can affect the outcome of the study.
References
Kozan, A., Yasak, R., & Akyol, M. (2020). A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris. Ttps://Doi.Org/10.1111/Dth.13534 . Retrieved 26 September 2020, from https://onlinelibrary.wiley.com/doi/full/10.1111/dth.13534.
Yadav, N., Singh, A., Chatterjee, A., & Belemkar, S. (2011). Evaluation of Efficacy and Safety of Perfect Face Gel and Perfect Face Tablets in Management of Acne. Journal Of Clinical & Experimental Anr Uoj Dermatology Research , 2 (2). Retrieved 26 September 2020, from https://www.longdom.org/open-access/evaluation-of-efficacy-and-safety-of-perfact-face-gel-and-perfact-face-tablets-in-management-of-acne-2155-9554.1000118.pdf.
